Cross-linked sulfonated polyacrylamide (Cross-PAA-SO3H) attached to nano-Fe3O4 as a superior catalyst for the synthesis of oxindoles
Authors
Abstract:
Cross-linked sulfonated polyacrylamide (Cross-PAA-SO3H) attached to nano-Fe3O4 as an efficientheterogeneous solid acid catalyst has been used for the preparation of spiro[pyrazoloquinoline-oxindoles]and spiro[chromenopyrazolo-oxindoles] through a four-component reactions of phenylhydrazineor hydrazine hydrate, isatins, ketoesters and naphthylamine or 2-naphthol under reflux conditions inethanol. The remarkable advantages of this methodology are easy work-up, short reaction times, highto excellent product yields, operational simplicity, low catalyst loading and reusability of the catalyst.
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Journal title
volume 6 issue 3
pages 185- 192
publication date 2019-09-01
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